「Nucleoside」に関連した動画の一覧 |
 | Nucleosides, Nucleotides & Nucleic Acids This webcast introduces the structure of the nucleic acids and their monomeric units, the nucleosides and nucleotides. 2010年12月14日再生回数 6554 |
 | Purine Nucleoside Phosphorylase Transition State Trajectory Depiction of the purine nucleoside phosphorylase (PNP) transition state trajectory. 2009年02月21日再生回数 1317 |
 | Nucleosides - - SciencePrimer video glossary More at: www.scienceprimer.com a nitrogenous base bound to a sugar, usually ribose or deoxyribose. Nucleosides are the precursors of nucleotides, the building blocks of DNA and RNA. Nucleotides are synthesized from nucleosides by the addition of one or more phosphates to the number 5 carbon of the sugar. 2012年03月10日再生回数 39 |
 | Bite-Sized Biochemistry #39 - Nucleotide Metabolism I Lecture by Kevin Ahern of Oregon State University discussing Biochemistry Basics in BB 451. See the full course at oregonstate.edu This course can be taken for credit (wherever you live) via OSU's ecampus. For details, see ecampus.oregonstate.edu Download Metabolic Melodies at www.davincipress.com Related courses include BB 350 - oregonstate.edu BB 450 - oregonstate.edu BB 100 - oregonstate.edu Nucleotide Metabolism 1. Nucleotides consist of a) sugar, b) nitrogenous base, and c) phosphate 2. Nucleosides consist of aa) sugar and b) nitrogenous base 3. The sugars of nucleosides and nucleotides are either ribose (found in ribonucleotides of RNA) or deoxyribose (found in deoxyribonucleotides of DNA). 4. The nitrogenous bases found in nucleotides include adenine (purine), guanine (purine), thymine (pyrimidine), cytosine (pyrimidine), and uracil (pyrimidine). 5. The bases adenine, guanine, and cytosine are found in both ribonucleotides and deoxyribonucleotides. Thymine is almost always found in deoxyribonucleotides. Uracil is found primarily in ribonucleotides and rarely in DNA, but does appear as a deoxyribonucleotide intermediate in thymidine metabolism. 6. Ribonucleotides are the building blocks of RNA and deoxyribonucleotides are the building blocks of DNA. 7. Nucleotides and nucleosides are made in cells by two general mechanisms - salvage pathways (use breakdown products of other nucleotides/nucleosides) or de novo pathways (synthesize nucleotides/nucleosides from scratch ... 2011年08月04日再生回数 2556 |
 | Etienne de Harven Vienna AIDS Conference 2010 www.science-and-aids.org Vienna AIDS Conference 2010 HERVs (Human Endogenous Retroviruses) are confounding factors in HIV/AIDS research that cannot be ignored. They account for the presence of retroviral nucleoside sequences in the plasma of AIDS patients, erroneously interpreted as HIV ?viral load?. They falsify claims of innumerable ?mutations? of the hypothetical HIV. They also provide a valid explanation for the presence of EM recognizable retroviruses in the original 1983 publication from the French Institut Pasteur. Understanding the interference of HERVs in AIDS research permits to confirm that an exogenous HIV, actually, does not exist, opening the way to the development of a fully re-directed, non-retroviral AIDS research. 2011年03月01日再生回数 739 |
 | 3D HIV Inhibitor Models Based from Tribute to HIV Inhibitors. Actually this was a tribute itself Please note that: Name at the bottom right corner is the one who responsible in the making of the video, skeletal structure and the pics Name at the bottom left corner is the one who/which responsible in the development and invention of the molecules and drugs Drugs are belong to respective owners, inventors and developers Pictures are self-made using BKchem, ACD 3D Viewer and Photoshop CS3 Pretty much for these singlets: xinorbis.deviantart.com I'll recompile the whole gallery into a movie once this has minimally 30 images in Molecular Structures AT 2008年10月05日再生回数 5254 |
 | Clip1 - sapala Organics Sapala has been successful in the multi-gram scale synthesis of Metal Complexes of bipyridines, terpyridines, porphyrins and phthalocyanines were made in multigram scale. Sapala has developed a Biotransformation process involving multi-gram scale enzymatic oxidation of amine group of nucleoside to keto group using "ADA" enzyme. we specialists in Analytical Chemistry and are capable of any analytical work related to Organic Synthesis 2011年06月15日再生回数 209 |
 | Bite-Sized Biochemistry #14: Enzyme Mechanism and Regulation Lecture by Kevin Ahern of Oregon State University discussing Biochemistry Basics in BB 450. See the full course at oregonstate.edu This course can be taken for credit (wherever you live) via OSU's ecampus. For details, see ecampus.oregonstate.edu Download Metabolic Melodies at www.davincipress.com Related courses include BB 350 - oregonstate.edu BB 451 - oregonstate.edu BB 100 - oregonstate.edu Highlights Catalytic Strategies (continued) 1. Restriction enzymes are paired with a methylase in bacterial cells. The methylase puts a methyl group on the same sequence the restriction enzyme would otherwise cut. When cellular DNA is protected in this way, the restriction enzyme cannot cut the cellular DNA, but it can cut invading viral DNA if it gets to it before the methylase does. 2. Restriction enzymes bind to DNA and "slide" along the double helix. When they reach the sequence they cut at (recognized by hydrogen bonds), the DNA is bent and a magnesium ion is allowed into the complex to facilitate the activation of water to nucleophilically attack the phosphodiester bond, cleaving it. 3. Kinases are enzymes that transfer phosphates onto molecules. They usually use ATP to do this. Nucleoside monophosphate kinases transfer phosphates onto nucleoside monophosphates. Adenylate kinase, for example, catalyzes the reaction ATP + AMP (in equilibrium with) ADP + ADP 4. One problem in the phosphate transfer is getting the phosphate onto the target molecule and not having it either ... 2011年06月10日再生回数 1241 |
 | HIV Replication 3D Medical Animation It is a very excellent animation which explains the hiv replication very clearly. For free download of this video please visit my webpage 3dmed.wetpaint.com And other 3D animation videos visit 3dmed.wetpaint.com Regards, Dr.Rufus The Lyrics of this video is here Targeting HIV replication The replication of HIV 1 is a multi-stage process. Each step is crucial to successful replication and is therefore a potential target of antiretroviral drugs. Step one is the infection of a suitable host-cell, such as a CD4-positive T-lymphocyte. Entry of HIV into the cell requires the presence of certain receptors on the cell surface, CD4 -- receptors and co-receptors such as CCR5 or CXCR4. These receptors interact with protein-complexes, which are embedded in the viral envelope. These complexes are composed of two glycoproteins: an extracellular gp 120 and a transmembrane gp 41 When HIV approaches the target cell gp120 binds to the CD4-receptors. This process is termed attachment. It promotes further binding to a co-receptor. Co-receptor binding results in a conformational change in gp120. This allows gp41 to unfold and insert its hydrophobic terminus into the cell membrane. Gp 41 then folds back on itself. This draws the virus towards the cell and facilitates the fusion of their membranes. The viral nucleocapsid enters the host cell and breaks open releasing two viral RNA-strands and 3 essential replication enzymes: Integrase, Protease and Reverse Transcriptase. Reverse Transcriptase ... 2007年03月04日再生回数 1071965 |
 | Using BrdU and Immunocytochemistry to analyze cell proliferation For more information visit: www.biomed-engineer.com This video explains the use of BrdU nucleoside and immunocytochemistry as a method to detect the fraction of cells that are proliferating in a culture. In this example two different cultures are compared, in two different media compositions: 1) complete media (DMEM, 10%FBS, 1%pen/strep) 2) differentiation media (DMEM, 4%FBS, 1%pen/strep) Explanation of technique: Use BrdU to bind to the DNA of cells in the S phase of the cycle Use Hoechst to bind to the DNA at any phase of the cell cycle Perform immunocytochemistry Primary antibody binds to cells that have incorporated BrdU Secondary antibody tagged with Alexa Fluor binds to the primary antibody and fluoresces Compare cells under Hoechst wavelength and under AlexaFluor wavelength to determine percentage of cells that are dividing. Music Attribution: "Cool Vibes" by Kevin MacLeod (incompetech.com) Creative Commons 3.0 2012年05月06日再生回数 34 |
